Session Detail


Session Number: 143
Session Title: Retina and RPE Cell Biology /
Session Type: Poster Session
Session Start: Sunday, May 01, 2011, 3:15 PM - 5:00 PM
Location: Hall B/C
Organizing Section: Retinal Cell Biology
Contributing Sections: Retina+
Program #/Board #: 898-937/A90-A129
Moderator-- B-A. Battelle. Whitney Laboratory, University of Florida, St Augustine, FL.
Presentations:
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 898/ A90. The Expression Of PPAR-gamma In RPE Cells Is Epigenetically Regulated By DNA Methylation
Shikun He1, Nymph Chan1, Jing Xu1, Peng Zhou1, S. J. Ryan1, David. R. Hinton1,2. 1Ophthalmology-USC, Doheny Eye Institute, Los Angeles, CA; 2Pathology, Keck school of Medicine at University of Southern California, Los Angeles, CA.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 899/ A91. Characterization Of Conditioned Media Collected From Aged Vs. Young Human Eye-cups
 Anton M. Kolomeyer, Ilene K. Sugino, Marco A. Zarbin. Ophthalmology and Visual Science, New Jersey Medical School-UMDNJ, Newark, NJ.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 900/ A92. Ultrasensitive Mass Spectrometric Analysis Of The Human Vitreous Proteome
 Tim U. Krohne1, Sebastian Aretz2, Boris V. Stanzel1, Martina Schnölzer3, Frank G. Holz1, Jürgen Kopitz2. 1Ophthalmology, University of Bonn, Bonn, Germany; 2Pathology, University of Heidelberg, Heidelberg, Germany; 3Functional Proteome Analysis, German Cancer Research Center, Heidelberg, Germany.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 901/ A93. Differentiation Of Human Retinal Pigment Epithelium Cells Into Multilineages
 Enrique Salero, Timothy A. Blenkinsop, Barbara Corneo, Jeffrey Stern, Sally Temple. Neural Stem Cell Institute, Rensselaer, NY.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 902/ A94. Sensitive and Specific Mass Spectrometric Identification and Quantitation of A2E
 Danielle B. Gutierrez1, Dan Higbee2, Kevin L. Schey3, Rosalie K. Crouch2, Zsolt Ablonczy2. 1Lab of Retinal Cell & Molecular Biol, NEI, Bethesda, MD; 2Ophthalmology, Medical Universtiy of South Carolina, Charleston, SC; 3Biochemistry, Vanderbilt, Nashville, TN.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 903/ A95. Protein S Is A Mer Ligand For Rpe-mediated Phagocytosis Of Photoreceptors In-vivo
Tal Burstyn-Cohen1, Greg Lemke2. 1Ophthalomology, Hadassah Medical Center, Jerusalem, Israel; 2Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 904/ A96. The Extracellular Part Of MerTK Is Shed By RPE Cells Both In Vitro And In Vivo
 Ah-Lai Law1, José A. Sahel1,2, Shomi S. Bhattacharya1,3, Emeline F. Nandrot1. 1INSERM, U968; UPMC Univ Paris 06, UMR_S 968, Institut de la Vision; CNRS, UMR_7210. 17 rue Moreau, F-75012, Paris, France; 2Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, INSERM-DHOS CIC 503, F-75012, Paris, France; 3University College London-Institute of Ophthalmology, London, United Kingdom.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 905/ A97. Melanosomes And Lipofuscin Granules Of The RPE Can Be Distinguished By Quantitative Analytical Electron Microscopy
 Antje K. Biesemeier1, Oliver Eibl2, Ulrich Schraermeyer1. 1University Eye Hospital, Section of experimental vitreoretinal Surgery, Tuebingen, Germany; 2University of Tuebingen, Institute of Applied Physics, Tuebingen, Germany.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 906/ A98. Investigation Of Protocadherin-21 Trafficking And Function In Transgenic Xenopus laevis Rod Photoreceptors
 Lee Ling Yang, Tami Bogea, Beatrice M. Tam, Orson L. Moritz. Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, BC, Canada.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 907/ A99. Role Of Mir-30b On The Regulation Of The Catalase Gene In Human ARPE-19 Cells
 Rashidul Haque, Dan Chen, Trisha Sengupta, Eugene Chun, Jennifer C. Howell, Hana Kim. Ophthalmology, Emory University, Atlanta, GA.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 908/ A100. Trp1-cre Revisited ; Evidence For Cre-recombinase Toxicity In The Retinal Pigment Epithelium
 Aristomenis Thanos, Yuki Morizane, Maki Kayama, Dimosthenis Mantopoulos, Yusuke Murakami, Lucy H. Young, Joan W. Miller, Demetrios G. Vavvas. Ophthalmology, Massachusetts Eye & Ear Infirmary, Boston, MA.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 909/ A101. Observation of Opsin Transport By Live Cell Imaging of Photoreceptors
 Mohammad Haeri, Barry E. Knox. Ophthalmology & Biochemistry & Molecular Biology, SUNY Upstate Medical University, Syracuse, NY.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 910/ A102. Lman1, Encoding ER-Golgi Transport Protein ERGIC-53, is a Direct Transcriptional Target of the Photoreceptor Transcription Factor NRL
 Janina Gregorski1, Hong Hao1, Douglas Kim2, Bin Zhang3, Anand Swaroop1. 1Neurobiology-Neurodegeneration and Repair Laboratory, NEI, Bethesda, MD; 2Howard Hughes Medical Institute, Ashburn, VA; 3Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 911/ A103. Withdrawn

Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 912/ A104. Effect Of Tissue-specific Disruption Of Porcupine On Mouse Eye Development
 Sabine Fuhrmann1A, Mary P. Colasanto1A, Charles Murtaugh1B, Elizabeth J. Bankhead1A. AOphthal & Vis Sci, BHuman Genetics, 1University of Utah, Salt Lake City, UT.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 913/ A105. Conditional Smad7 Knockdown Causes Elevated Number Of Müller Glia And Increased Nestin Expression In The Central Retina
 Martina Klupp1,2, Rudolf Fuchshofer1, Barbara Braunger1, Ernst R. Tamm1, Ludwig Aigner2. 1Institute of Human Anatomy and Embryology, University of Regensburg, Regensburg, Germany; 2Institute of Molecular Regenerative Medicine, Paracelsus Medical University, Salzburg, Austria.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 914/ A106. The Atypical Cadherin Fat3 Regulates Amacrine Cell Morphology and Retinal Lamination
 Michael Deans1, Andrew Tucker2, Catherine Copley1, Lisa Goodrich2. 1Otolaryngology, Johns Hopkins University, Baltimore, MD; 2Neurobiology, Harvard Medical School, Boston, MA.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 915/ A107. Inhibition Of Muller Cell Circadian Rhythms By siRNA Knockdown Of Period Genes
 Lili Xu1, Tianyu Xu2, Guoxiang Ruan3, Douglas G. McMahon1. 1Biological Science, Vanderbilt University, Nashville, TN; 2Georgia Institute of Technology, Atlanta, GA; 3Schepens Eye Institute, Harvard University, Boston, MA.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 916/ A108. Long-term Dark Adaptive Biochemistry Of Photoreceptors Is Influenced By Time Of Day
 B-A. Battelle, A Parker, C. Gaddie, K. Kempler. Whitney Laboratory, University of Florida, St Augustine, FL.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 917/ A109. Circadian Clock Gene Knockout Mice Display Decreased Photoreceptor Phagocytic Turnover
 Ouafa Ait-Hmyed, Marie-Paule Felder-Schmittbuhl, David Hicks. Neurobiology of Rhythms, CNRS UPR 3212, Strasbourg, France.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 918/ A110. Ozone Decreases Dopamine Levels and Disrupts the Circadian Clock in the Rat Retina
 Rejeana M. Stephens1, Paige C. McIntyre1, Rajat Sethi2, Carlos A. Garcia1. 1Biological and Health Sciences, Texas A&M University Kingsviile, Kingsville, TX; 2Pharmaceutical Sciences, Texas A&M Health Science Center, Kingsville, TX.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 919/ A111. Serotonin Receptor Expression In The Rodent Retina
 Keith V. Michaels, Jonathan W. Stoddard, Emily D. Blum, Anastasiya Maricle, Evangeline Zhou, Mark E. Pennesi, Peter J. Francis. Ophthalmology, OHSU Casey Eye Institute, Portland, OR.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 920/ A112. Interaction of 7R and Rootletin in Mouse Photoreceptors
 Yekaterina Gribanova, Novrouz B. Akhmedov, Debora B. Farber. Jules Stein Eye Institute, UCLA School of Medicine, Los Angeles, CA.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 921/ A113. The Photoisomerase Retinal G Protein Coupled Receptor (RGR) Is Localized In The Ganglion Cell Layer Of The Chicken Retina
 Nicolas M. Diaz, Sr., Diego J. Valdez, Daniela M. Verra, Mario E. Guido. CIQUIBIC-Departamento de Química Biológica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Cordoba, Argentina.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 922/ A114. Expression Of Histone Acetyl Tranferases And Deacetylases In Murine Retinal Astrocytes
 Mahesh Shivanna1, Nader Sheibani2, Teri Belecky-Adams1. 1Biology and Regenerative Medicine, IUPUI, Indianapolis, IN; 2Ophthalmology and Visual Sciences, Univ of Wisconsin-Madison, Madison, WI.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 923/ A115. Characterization Of The Crb3 Protein In The Mouse Retina
 Concepcion Lillo, Saúl Herranz, Antonio E. Paniagua, Almudena Velasco, Juan M. Lara, José Aijón. Cell Biology and Pathology, INCyL, University of Salamanca, Salamanca, Spain.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 924/ A116. Withdrawn

Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 925/ A117. Role Of Ferroportin In Rpe Iron Export
 Jared Iacovelli1, Majda Hadziahmetovic1, Ying Song1, Steven Grieco1, Irene Zohn2, Joshua L. Dunaief1. 1FM Kirby Ctr, Scheie Eye Insitute, University of Pennsylvania, Philadelphia, PA; 2Neuroscience Research Department, Children National Medical Center, Washington, DC.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 926/ A118. Investigations of Two-photon Excited Bright Autofluorescent Granules in the RPE Cells Around Photocoagulation Spots
 Yoko Miura1A, Gereon Hüttmann1A, Regina Orzekowsky-Schroeder1A, Philipp Steven1B,1C, Márta Szaszák1D, Novert Koop1A, Reginald Birngruber1A, Ralf Brinkmann1A. AInstitute of Biomedical Optics, BDepartment of Ophthalmology, CInstitute of Anatomy, DInstitute of Medical Microbiology and Hygiene, 1University of Luebeck, Luebeck, Germany.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 927/ A119. The beta-Hydroxybutyrate Receptor GPR109A Functions as an Anti-inflammatory Receptor In Retinal Pigment Epithelium (RPE)
 Deeksha Gambhir1A, Sudha Ananth1A, Muthusamy Thangaraju1A, Nevin Lambert1B, Eric Jennings1C, Julian J. Nussbaum1C, Sylvia B. Smith1D, Stefan Offermanns2, Vadivel Ganapathy1E, Pamela M. Martin1E. ABiochemistry/Molecular Biology, BPharmacology and Toxicology, COphthalmology, DCellular Biology and Anatomy, EBiochemistry and Molecular Biology, 1Medical College of Georgia, Augusta, GA; 2Institute of Pharmacology, University of Heidelberg, Heidelberg, Germany.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 928/ A120. Transport via Slc5a8 (SMCT1) is Obligatory for 2-Oxothiazolidine-4-carboxylate to Enhance Glutathione Production in Retinal Pigment Epithelial Cells
 Pamela M. Martin1A, Ellappan Babu1A, Rajalakshmi Veeranan-Karmegan1A, Veena Coothankandaswamy1A, Sylvia B. Smith1B, Thomas Boettger2, Vadivel Ganapathy1A. ABiochemistry and Molecular Biology, BCellular Biology and Anatomy, 1Medical College of Georgia, Augusta, GA; 2Cardiac Development and Remodeling, Max-Planck Institue fuer Herz-und Lundgenforschung, Bad Nauheim, Germany.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 929/ A121. Expression and Iron-dependent Regulation of Succinate Receptor GPR91 in Retinal Pigment Epithelium
 Jaya Pranava Gnana Prakasam1A, Sudha Ananth1A, Puttur D. Prasad1A, Ming Zhang1B, Sally S. Atherton1B, Pamela M. Martin1A, Sylvia B. Smith1B, Vadivel Ganapathy1A. ABiochemistry and Molecular Biology, BCellular Biology and Anatomy, 1Medical College of Georgia, Augusta, GA.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 930/ A122. Evaluation Of The Effect Of Thrombin On The Structure Of Tight Junctions And The Permeability Of RPE And Endothelial Cells
 Tami Livnat1, Omer Bialer1, Yael Nisgav1, Rima Dardik1, Dov Weinberger1,2. 1Department of Ophthalmology, Rabin Medical Center, Petah Tiqwa, Israel; 2Tel-Aviv University School of Medicine, Tel-Aviv, Israel.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 931/ A123. Characterization of Transgenic Mouse RPE Cultures
 Nicole R. Congrove, Christina L. Decatur, J. Brett Stanton, Alan D. Marmorstein, Brian S. McKay. Ophthalmology, The University of Arizona, Tucson, AZ.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 932/ A124. A Histoimmunochemistry-assisted Method For Evaluation Of Retinal Pigment Epithelium (RPE) Within An Intact RPE-Bruch’s Membrane-choriocapillaris Complex
 Lixia Lu1, Jingfa Zhang1, Weiye Li2, Guo-Tong Xu1. 1Tongji Eye Institute, Tongji University School of Medicine, Shanghai, China; 2Ophthalmology, Drexel University College of Medicine, Philadelphia, PA.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 933/ A125. Assay For Establishment Of Highly Polarized Porcine Retinal Pigment Epithelial Cells
 Shozo Sonoda1, Makoto Shirasawa1, Hiroki Otsuka1, Toshio Hisatomi2, Noboru Arimura1, Yasushi Sonoda1, Taiji Sakamoto1. 1Department of Ophthalmology,Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan; 2Department of Ophthalmology, Kyushu University, Graduate School of Medical Sciences, Fukuoka, Japan.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 934/ A126. A Novel Type Of Lysosome Identified In The Retinal Epithelium Of Young Rhesus Monkeys
Peter Gouras1, Lena M. Ivert2, Martha Neuringer3, Julie Mattison4. 1Ophthalmology/Eye Institute, Columbia University, New York, NY; 2Ophthalmology, Karolinska Institute, Stockholm, Sweden; 3Neuroscience & Ophthalmology, Oregon Health & Science University, Beaverton, OR; 4Laboratory of Experimental Gerontology, National Institute on Aging, Poolesville, MD.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 935/ A127. In Vitro Comparison Of Structural And Functional Characteristics Of Cultured Autologous Monolayer Sheets Of Iris Pigmentary Epithelial And Retinal Pigmentary Epithelial Cells
 Gibran S. Khurshid, Tomasz A. Wiraszka, Kapil G. Kapoor, Praveena Gupta. Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch, Galveston, TX.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 936/ A128. Integrin Activation Increases RPE Adhesion To Bruch’s Membrane Components And Overcomes Tenascin-C-mediated Failure Of Adhesion In The Rat
 Janosch P. Heller1A, James W. Fawcett1A, Keith R. Martin1B,1C. ACentre for Brain Repair, BDepartment of Ophthalmology, CNIHR Biomedical Research Centre, 1University of Cambridge, Cambridge, United Kingdom.
Sunday, May 01, 2011, 3:15 PM - 5:00 PM
 937/ A129. Inhibition Of Rho-kinase Counteracts The Proliferation, Motility, Contraction, And Dedifferentiation Of Retinal Pigment Epithelial Cells (RPEs)
 Aysegul Tura1, Farid Abdel Aal1, Martin Rudolf1, Sigrid Henke-Fahle2, Salvatore Grisanti1, Matthias Lueke1. 1Department of Ophthalmology, University of Luebeck, Luebeck, Germany; 2University Eye Hospital, Center of Ophthalmology at the Eberhard-Karls University, Tuebingen, Germany.
 




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