Presentation Abstract

Session: SE63-SE78-Sports Medicine/Arthroscopy Scientific Exhibits
Date/Time: Friday, Mar 22, 2013, 7:00 AM - 6:00 PM
Scientific Exhibits occur Tuesday through Saturday.
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Location McCormick Place, Academy Hall B
Presentation Number: SE69
Title: Children Exposed to Increased Exercise Gain Skeletal Benefits Without Any Increase in Fracture Risk
Classification: +Basic Science/Biologics (Sports Med/Arthro)
Keywords: Trauma / Fractures; Basic Science / Tumor / Infection; MRI / Imaging
Author(s): Fredrik T. Detter, MD, Malmo, Sweden
Bjorn Rosengren, MD, PhD, Malmo, Sweden
Jan-Ake Nilsson, BSc, Malmo, Sweden
Magnus Dencker, MD, PhD, Malmö, Sweden
Magnus Karlsson, MD, Malmo, Sweden
Abstract: Introduction:
Pediatric exercise intervention studies that evaluate if physical activity can decrease facture risk span maximum 36 months and use bone traits as a surrogate endpoint for fractures. It is however essential to include also fractures as an end point variable as high level of physical activity has been reported to be associated with high fracture risk.
Methods:
During 6 years we conducted a population based controlled exercise intervention study in 362 girls and 446 boys in the intervention group (3515 person-years) and 780 girls and 807 boys in the control group (7628 person-years), all aged 7-9 years at baseline. Children in the intervention group received 40 minutes of daily physical education (PE) while the control group continued with the Swedish standard of 60 minutes PE per week. Incident fractures were registered in all 2395 children. Skeletal development was followed annually by dual energy X-ray absorptiometry (DXA) in 78 girls and 113 boys in the intervention group and 53 girls and 54 boys in the control group. Slopes and annual changes were calculated for bone mineral density (BMD; g/cm2) and femoral neck (FN) area (mm2). Data are reported as mean group differences with 95% CI within brackets.
Results:
There were 20.5 fractures/1000 person-years in the intervention group and 18.8 fractures/1000 person-years in the control group, resulting in a Rate Ratio (RR) of 1.09 (0.81, 1.45). The annual gain in spine BMD was higher in both girls (0.007 (0.001, 0.013g /cm2)) and boys (0.004 (0.001, 0.008 g /cm2)) in the intervention compared to the control group and girls with daily PE also had higher gain in femoral neck area (0.04 (0.01, 0.07 mm2)).
Discussion and Conclusion:
Increased physical activity for 6 years in a population based cohort of 7-9 year old children induce higher gain in bone mass and in girls also improved skeletal size without increasing the fracture risk.



Disclosures: Presenting Author
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