Presentation Abstract

Title: P10.62 - Genetic structure of Western Caucasus populations on the base of uniparental polymorphisms
Keywords: Western Caucasus; Y-chromosome; mitochondrial DNA
Authors: S. Litvinov1, E. Khusnutdinova1, I. Kutuev1, R. Khusainova1, R. Valiev1, R. Villems2;
1Institute of Biochemistry and Genetics of Ufa Science Center of Russian Academy of Sciences, Ufa, Russian Federation, 2Department of Evolutionary Biology, University of Tartu, Tartu, Estonia.
Abstract Body: The populations of western part of the Caucasus represent significant historical, ethno-cultural and linguistic traits. We have analyzed 52 markers in coding region of the mtDNA and 48 markers in the non-recombining part of the Y-chromosome in 592 individuals representing five populations from western Caucasus (Abkhazians, Adyghes, Abazins, Georgians, and Circassians). Y-chromosome haplogroups G-M201 and J2 (J-M172) account for more than 50% of all haplogroup diversity in the studied populations. Haplogroup G-M201 in the Western Caucasus populations is represented only by subclade G2a (G-P15) with the insignificantly low exception in the Adyghe population where G1a (G-P20) amounts to less than 1%. In contrast to high frequency of J2 haplogroup J1 exhibit moderate occurrence and vary from 2 to 6 %. Haplogroup R1a (R-SRY10831.2) is also present in all studied populations. It is difficult to say though whether this component is a result of Eastern European influence or it has arrived from other source. While analysis of the coding region with high level of resolution is needed to understand the source of high frequencies of haplogroup H, occurrence of haplogroup U subclades slightly differs in all 5 populations.