Session Detail


Session Title: Human Papillomavirus: Beyond Cervical Cancer
Session Type: Current Concepts in Epidemiology and Prevention Research
Session Start/End Time: Tuesday, Apr 09, 2013, 10:30 AM -12:30 PM
Location: Room 152, Washington Convention Center
CME: CME-Designated
CME/CE Hours: 2
Session Description: Persistent infection with oncogenic human papillomavirus (HPV) is a necessary cause of virtually all cervical cancers and for defined subsets of vaginal, vulvar, penile, anal and oropharyngeal cancers. Cervical cancer prevention by means of prophylactic vaccination against and screening to detect HPV infection is one of the most significant advances in the history of cancer prevention, and yet, worldwide over 600,000 cancers are caused by HPV each year. Two licensed preventive HPV vaccines demonstrate the possibility of dramatically reducing rates of cervical and other anogenital cancers, but their efficacy against oropharyngeal cancers is unknown. Additionally, many barriers to global reduction in cervical cancer, including type-restricted immunity, vaccine cost and delivery method. Unvaccinated cohorts bear a substantail burden of non-cervical HPV-associated cancers due to the absence of validated screening methods for these cancers. Despite the availability of preventive vaccines against the cancer associated HPVs, there is a need for therapeutic options targeting HPV-associated cancers and the persistent infections that give rise to these cancers. Interfering with the functions of the viral E6 and E7 oncogenes provide therapeutic opportunities that are being explored.
Presentations:
Chairperson
Tuesday, Apr 09, 2013, 10:30 AM -12:30 PM
Maura L. Gillison. Ohio State Univ. Comp. Cancer Ctr., Columbus, OH
Prevention of non-cervical HPV-associated cancers
Tuesday, Apr 09, 2013, 10:30 AM -10:50 AM
Aimee Kreimer. National Cancer Inst., Bethesda, MD
Discussion
Tuesday, Apr 09, 2013, 10:50 AM -10:55 AM
The science of next generation HPV vaccines
Tuesday, Apr 09, 2013, 10:55 AM -11:15 AM
Richard B. Roden. Johns Hopkins Univ., Baltimore, MD
Discussion
Tuesday, Apr 09, 2013, 11:15 AM -11:20 AM
HPV E6/E7 oncoproteins as targets for therapy of HPV-associated cancers
Tuesday, Apr 09, 2013, 11:20 AM -11:40 AM
Peter M. Howley. Harvard Medical School, Boston, MA
Discussion
Tuesday, Apr 09, 2013, 11:40 AM -11:45 AM
The HPV "virome" in head and neck cancers
Tuesday, Apr 09, 2013, 11:45 AM -12:05 PM
Maura L. Gillison. Ohio State Univ. Comp. Cancer Ctr., Columbus, OH
Discussion
Tuesday, Apr 09, 2013, 12:05 PM -12:10 PM
Panel Discussion
Tuesday, Apr 09, 2013, 12:10 PM -12:30 PM