Session Detail


Session Title: Breast Cancer: Progress in Basic and Translational Research
Session Type: Current Concepts in Organ Site Research
Session Start/End Time: Sunday, Apr 06, 2014, 1:00 PM - 3:00 PM
Location: Room 6A, San Diego Convention Center
CME: CME-Designated
CME/CE Hours: 2
Session Description: This session will include four presentations that will cover the spectrum of bench to bedside and back to bench investigation of high relevance to breast cancer biology, genomics, and mechanism-based clinical investigation. Topics will include use of genetically-engineered mouse models for therapeutic research, aspects of tumor heterogeneity and plasticity, genomic profiling of mouse and human breast cancers, and the latest on the clinical development of PI3K/TOR pathway inhibitors for patients with breast cancer.
Presentations:
Chairperson
Sunday, Apr 06, 2014, 1:00 PM - 3:00 PM
Carlos L. Arteaga. Vanderbilt-Ingram Cancer Ctr., Nashville, TN
Unraveling therapy resistance in mouse models of breast cancer
Sunday, Apr 06, 2014, 1:00 PM - 1:20 PM
Jos Jonkers. Netherlands Cancer Inst., Amsterdam, Netherlands
Discussion
Sunday, Apr 06, 2014, 1:20 PM - 1:25 PM
Cellular plasticity and lineage infidelity drive breast cancer heterogeneity
Sunday, Apr 06, 2014, 1:25 PM - 1:45 PM
Charlotte Kuperwasser. Tufts Univ. School of Medicine, Boston, MA
Discussion
Sunday, Apr 06, 2014, 1:45 PM - 1:50 PM
Genomic and genetic analysis of human and murine mammary cancers
Sunday, Apr 06, 2014, 1:50 PM - 2:10 PM
Charles M. Perou. Univ. of North Carolina at Chapel Hill, Chapel Hill, NC
Discussion
Sunday, Apr 06, 2014, 2:10 PM - 2:15 PM
PI3K/TOR pathway: Role in breast cancer progression and as a therapeutic target_
Sunday, Apr 06, 2014, 2:15 PM - 2:35 PM
Carlos L. Arteaga. Vanderbilt-Ingram Cancer Ctr., Nashville, TN
Discussion
Sunday, Apr 06, 2014, 2:35 PM - 2:40 PM
NG01: Blockade of EGFR and HER3 enhances PI3K/Akt antitumor activity in triple negative breast cancer
Sunday, Apr 06, 2014, 2:40 PM - 2:55 PM
Maurizio Scaltriti, Jessica Tao, Pau Castel, Nina Radosevic-Robin, Moshe Elkabets, Neil Auricchio, Dejan Juric, Frédérique Penault-Llorca, Jose Baselga. Memorial Sloan-Kettering Cancer Center, New York, NY, Massachusetts General Hospital Cancer Center, Boston, MA, University of Auvergne, Clermont-Ferrand, France
Discussion
Sunday, Apr 06, 2014, 2:55 PM - 3:00 PM