Presentation Abstract

Program#/Poster#: 475.09/II15
Presentation Title: Smart-e-Pants: A novel neural prosthetic device for the prevention of deep tissue injury in spinal cord injury and other neurological disorders
Location: Hall F-J
Presentation time: Monday, Oct 15, 2012, 1:00 PM - 2:00 PM
Authors: R. A. WARWARUK ROGERS1, A. AHMETOVIC4, D. SCHNEPF8, R. SOMMER9, L. KAWASAKI5, G. ISSACSON9, V. MUSHAHWAR6, M. CHAN7, *S. P. DUKELOW1,2,3;
1Clin. Neurosciences, 2Hotchkiss Brain Inst., 3Fac. of Med., Univ. of Calgary, Calgary, AB, Canada; 4Ctr. for Neurosci., 5Dept. of Pharmacol., 6Dept. of Cell Biol., 7Fac. of Med. and Dent., Univ. of Alberta, Edmonton, AB, Canada; 8Allen Gray Continuing Care Ctr., Edmonton, AB, Canada; 9Glenrose Rehabil. Hosp., Edmonton, AB, Canada
Abstract: Pressure ulcers (PU), specifically deep tissue injury (DTI) are a common complication in people with reduced mobility such as those with spinal cord injury. DTI originates in the muscle layer around a bony prominence, resulting from unrelieved loading causing sustained mechanical deformation and ischemia to the underlying tissue. PU’s decrease health status, mobility, increase pain, and may require invasive surgical reconstruction procedures of the affected area and can be fatal. Despite advances in pressure relieving strategies, DTI continues to impact patient health negatively and contributes substantial costs to the healthcare system. In this study, we examined the safety and feasibility of a novel prevention system for DTI: Smart-e-Pants. The Smart-e-Pants system
is a neural prosthetic device that involves a stimulator designed to deliver
intermittent electrical stimulation (IES) via electrodes placed directly on the skin or through an engineered garment. The electrodes are applied over the motor point of the gluteus maximus muscle. Simulation causes contraction of the gluteus maximus to mimic the subconscious “fidgeting” movements of able bodied people. Previous studies in animals have demonstrated significant increases in tissue oxygenation and pressure redistribution in response to IES. The aim of the Smart-e-Pants device is to prevent the development of DTI in individuals with spinal cord injury and others with immobility.
In the present study the Smart-e-Pants system was tested in a variety of patient care settings. Subjects with immobility (n=23) wore Smart-e-Pants
and received IES for 12 hours a day, 4 days per week, for 4 weeks to induce muscle contractions in the gluteus maximus. The system administered stimulation for 10 seconds at 10 minute intervals during periods when subjects wore the garment. We assessed the system for safety and feasibility during periods of garment application and removal by quantifying patient and healthcare staff responses to measures of time demands for application and removal, acceptability for participant and caregiver, skin irritation, and muscle contraction stability.
Smart-e-Pants received positive ratings from both patients and healthcare staff. The system was generally safe and the time demands were reasonable for application and removal. No one in the present study developed a PU during the experimental period. Our results suggest that IES may be an acceptable method for the prevention of PU’s, but further efficacy studies are necessary.
Disclosures:  R.A. Warwaruk Rogers: None. A. Ahmetovic: None. D. Schnepf: None. R. Sommer: None. L. Kawasaki: None. G. Issacson: None. V. Mushahwar: Ownership Interest; Prev Bio Tech, subsidiary of Biomotion. M. Chan: None. S.P. Dukelow: None.
Keyword(s): SPINAL CORD INJURY
ELECTRICAL STIMULATION
MUSCLE
Support: AIHS Team Grant awarded to Interdisciplinary Team in Smart Neural Protheses
[Authors]. [Abstract Title]. Program No. XXX.XX. 2012 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2012. Online.

2012 Copyright by the Society for Neuroscience all rights reserved. Permission to republish any abstract or part of any abstract in any form must be obtained in writing by SfN office prior to publication.




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