Presentation Abstract

Session: 01-Obesity
Wednesday, Mar 23, 2011, 8:45 AM -10:00 AM
Presentation: 003 - Short Sleep Duration Increases Energy and Fat Intakes in Normal Weight Men and Women
Location: Atrium Ballroom A
Pres. Time: Wednesday, Mar 23, 2011, 9:45 AM -10:00 AM
Category: +NPAM - Obesity
Keywords: Diet; Obesity; Nutrition
Author(s): Marie-Pierre St-Onge, Amy L Roberts, Sari Tepper, Michael Kelleman, Majella O'Keeffe, Andrew McReynolds, Columbia Univ, New York, NY
Abstract: Introduction: There is evidence suggesting a relationship between sleep duration and obesity. However, few studies have measured food intake under periods of short and regular sleep.
Hypothesis: We hypothesized that reducing sleep duration, in normal sleepers, would lead to greater overall energy intakes relative to regular sleep.
Methods: We conducted a randomized cross-over inpatient study in which subjects were tested during 2 phases of 6 d each: short sleep (4 h/night in bed) and regular sleep (9 h/night in bed). All subjects had a body mass index 22-25 kg/m2 and slept, on average, 7-9 h/night. During the first 4 d of each phase, subjects consumed a controlled diet. During the last 2 d of each phase, food intake was self-selected and measured. Macronutrient and energy intakes were assessed using diet analysis software. Data from d 6 were removed from the analyses because subjects were discharged that evening and their total intake could not be ascertained. Food intake on d 5 was under supervision and could be completely assessed for each subject.
Results: A total of 13 men and 13 women were included in the analyses. Subjects consumed more calories during short sleep than regular sleep (295.6 ± 123.6 kcal, P = 0.03). This effect was mostly due to increased consumption of fat (20.7 ± 7.5 g, P = 0.01), notably saturated fat (8.7 ± 4.0 g, P = 0.04), during the period of short sleep compared to regular sleep. There was a trend for greater consumption of protein as well (9.9 ± 5.4 g, P = 0.08). Although there was no significant sleep duration by gender interaction, we analyzed our data separately by gender because of main effects or trends for main effects of gender in some of our models. These analyses tended to show a more pronounced effect of short sleep duration on energy intakes in women as they ate an average of 328.6 ± 174.5 kcal more during short sleep compared to regular sleep (P = 0.07) whereas men tended to eat 262.7 ± 176.7 kcal more during short sleep (P = 0.15). Similarly, women consumed 30.7 ± 10.5 g (P = 0.04) more fat on short compared to regular sleep whereas men had no difference in fat intake between sleep phases (regular compared to short = -10.6 ±10.7 g, P = 0.33). There was no significant effect of sleep on carbohydrate, sugar, sodium, or fiber intakes.
Conclusion: Our data show that reducing sleep increases energy and fat intakes, which may explain some of the association observed between sleep and obesity. If sustained, the dietary choices made by individuals undergoing short sleep would predispose one to obesity and increased risk of cardiovascular disease.
Disclosures:  M. St-Onge: None. A.L. Roberts: None. S. Tepper: None. M. Kelleman: None. M. O'Keeffe: None. A. McReynolds: None.