Presentation Abstract

Session: P02-Nutrition
Wednesday, Mar 23, 2011, 5:00 PM - 7:00 PM
Presentation: P152 - Heart Healthy Diet and Incident Impaired Fasting Glucose and Type 2 Diabetes in American Indians: The Strong Heart Family Study
Location: P152
Pres. Time: Wednesday, Mar 23, 2011, 5:00 PM - 7:00 PM
Category: +EPI - Nutrition
Keywords: Diet; Diabetes mellitus
Author(s): Amanda M Fretts, Univ of Washington, Seattle, WA; Barbara V Howard, MedStar Health Res Inst, Washington, DC; Barbara McKnight, Glen E Duncan, Shirley A Beresford, Univ of Washington, Seattle, WA; Mihriye Mete, MedStar Health Res Inst, Washington, DC; Sigal Eilat-Adar, Zinman Coll for Physical Education & Sports, Wingate Inst, Netanya, Israel; David S Siscovick, Univ of Washington, Seattle, WA
Abstract: Objective: To examine the associations of a heart healthy diet with incident impaired fasting glucose (IFG) and diabetes among American Indians.
Methods: The study population included participants from the Strong Heart Family Study who were free of diabetes (n = 2001) or IFG (n =1667) at baseline and participated in a follow-up examination. Information on diet was collected at baseline using a Block food frequency questionnaire. A diet quality score was computed using seven dietary components shown to be associated with a heart healthy diet (intake of vegetables, fruit, nuts/soy products, cereal fiber, trans fat, ratio of white to red meat, and ratio of polyunsaturated fat to saturated fat). Based on frequency of intake of each of these foods, participants received a dietary score ranging from 0 (worst diet) to 70 (best diet). Incident diabetes was defined based on 2003 ADA criteria. To account for within-family correlation, generalized estimating equations were used to examine the associations of dietary scores (in quartiles) with incident IFG and diabetes, after adjustment for potential confounders.
Results: We identified 412 cases of IFG and 243 incident cases of diabetes during an average follow-up of five years. Dietary scores ranged from 8.0-57.9. Compared with participants in the lowest quartile, those with higher intake had a lower risk of IFG and diabetes after adjustment for age, sex, site, education, smoking, alcohol use, and total caloric intake (Table 1). Further adjustment for steps/day or BMI did not attenuate the relative risk estimates.
Conclusions: The findings suggest that a heart healthy diet is associated with a lower risk of diabetes in American Indians. Diet quality should be emphasized as a major component of public health interventions to reduce diabetes risk among American Indians.
Disclosures:  A.M. Fretts: None. B.V. Howard: None. B. McKnight: None. G.E. Duncan: None. S.A.A. Beresford: None. M. Mete: None. S. Eilat-Adar: None. D.S. Siscovick: None.