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P17.5 - Y chromosome haplogroup analysis to estimate genetic origin of Balts
Y haplogroups; ethnogenetics; Balts
, L. Pliss
, L. Piekuse
, S. Limborska
, A. Krumina
Riga Stradins University, Laboratory of Molecular Genetics, Riga, Latvia,
Latvian Biomedical Research and Study Centre, Riga, Latvia,
Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, Russian Federation.
To obtain a more accurate portrait of ancestry of Balts Y chromosome haplogroupe (Y-hg) structure was determined in Russian individuals that inhabit historical regions of Baltic tribes and compared with incidence of Y-hg in Latvian population.
Material and methods.
A study comprised 192 men - representatives of four Northern-Western Russian regions (Mezen, Ustyuzhna, Sychevka, Starista) and 153 men representing Latvian subpopulations. To establish Y haplogroups DNA samples were hierarchically genotyped (using appropriate PCR followed by RFLP or sequencing) by 13 Y chromosomal binary markers (M9, SRY-1532, M17, Tat, M178, M170, P37, M253, M223, M172, YAP, M35, M201).
Results and discussion.
It was found that distribution of major Y-hg’s was relatively homogenous among analysed Russian and Latvian subpopulations. Only Russian subpopulation Mezen (Archangelsk district) showed the lowest frequency of the Slavic component
representing R1a haplogroup (22.5%) in comparison to other Russian (~55%) and Latvian (~40%) subpopulations. On the other hand the Fino-Ugric speaking population representing haplogroup N1c was the most common in Mezen (51%) in comparison to other Russian (~15%) and Latvian (~45%) subpopulations. Principal component analysis revealed that haplogroup N1c links Mezen with Eastern Latvian subpopulations Semigalians and Letigalians in one cluster, representing the hypothesis that the genetic history of N1c Y chromosomes in Baltic-speaking populations is distinct from that of the Uralic speakers.
Findings indicate that there are no significant differences in common Y-hg distribution among analysed Russian and Latvian subpopulations; however the analysis of Y-Hg genofund in Mezen indicates possible Fino-Ugric or Baltic ancestry.
The European Society of Human Genetics 2013
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