THE ESHG PROGRAMME PLANNER
J16.14 - In Search of the Origin of Haplogroup J1-P58
Haplogroup J1-P58; Armenian Highland; Origin
, H. Sahakyan
, M. Haber
, A. Bahmanimehr
, S. Rootsi
, P. Zalloua
, R. Villems
, L. Yepiskoposyan
Institute of Molecular Biology, Yerevan, Armenia,
University of Tartu and the Estonian Biocentre, Tartu, Estonia,
The Lebanese American University, Beirut, Lebanon.
Y-chromosomal haplogroup J1, one of the most frequent male lineages in the Near East, is believed to have originated around 10-15 kya in Northern Mesopotamia. J1 along with R1b and J2is generally considered as a genetic marker for the Neolithic expansion, therefore the study of its origin and spread is essential for tracing back ancient human migrations and expansions from the Near-East. In this study, we report a new potential source population and geographic location for the origin of J1-P58, a major sub-clade of haplogroup J1.
Previous studies did not explore the region of Armenian Highland when investigating J1-P58 origin. For this study we have genotyped 453 Armenian samples representing eastern, central and western parts of the highland, 297 Azeri and102 Qashqai samples from Iran, as well as used already published results of different comparative data sets.
The highest J1-P58 variance was observed in the Armenian population from the central part of the highland (regions of Alashkert and Bayazet). The mean age of J1-P58 in this region based on 8 STR markers, was estimated to be the oldest among the studied populations, dating back to 19.4 ky when using the evolutionary mutation rates. It is worth mentioning that the obtained result is based on the analysis of one ethnically homogenous territorial group located in a geographically restricted region in the central part of the Armenian plateau. We believe that this approach leads to better time estimates and significantly narrows down the geographic area where J1-P58 could have originated.
The European Society of Human Genetics 2013
The Online Abstract Submission and Invitation System
© 1996 - 2015 Coe-Truman Technologies, Inc. All rights reserved.