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J16.78 - The gene pool of Argyn in the context of generic structure of Kazakhs according to data on SNP-Y-Chromosome markers.
Y-chromosom; Kazakh tribe of Argyn; Genographic
, Z. Sabitov
, I. Tazhigulova
, P. Tarlykov
, Y. Yusupov
, K. Dibirova
, P. Nymadawa
, E. Balanovska
, I. Zakharov
, O. Balanovsky
Center for Life Sciences, Nazarbayev University, Astana, Kazakhstan,
Vavilov Institute of General Genetics RAS, Moscow, Russian Federation,
Gumilyov Eurasian National University, Astana, Kazakhstan,
Forensic science centre of the Ministry of Justice of the Republic of Kazakhstan, Astana, Kazakhstan,
National Center for Biotechnology of the Republic of Kazakhstan, Astana, Kazakhstan,
Institute for Humanities Research of the Republic of Bashkortostan, Ufa, Russian Federation,
Research Centre of Medical Genetics RAMS, Moscow, Russian Federation,
Mongolian Academy of Sciences, Ulaanbaatar, Mongolia.
Study of Y-chromosome polymorphism with consideration of the genealogical structure provides information about the history and the fine structure of gene pool, and it can help identify major patterns of variation in gene pool, determination of migration routes, and genetic boundary between the relatively homogeneous gene pools.
The study was performed on the Kazakh tribe of Argyn, which are included in the three “Juz” (ethno-territorial entities of Kazakh tribes) in the "Shezhire" system of Kazakhs. The Shezhire system characterizes the tribal structure of the Kazakh people, which was the ethno-social basis of social organization. It is therefore important to examine the association of Y-chromosome variability with the genealogical structure, and clarify the relationship between biological and social kinship.
We analyzed 40 SNP and 17 STR Y-chromosomal markers. In the study, besides the descendants of Argyn (sample size N = 287), 14 tribes of Kazakhs and 12 tribes Mongolians (in all N = 2186) were analyzed. In the tribe of Argyn, twenty haplogroups were identified, among which there were one major haplogroups - G1a - P20 (71%) and three minor haplogroups R1a* - M198(xM458) (6%), C3c - M48 (5%) and C3* - M217(xM48) (3%). Other haplogroups represent less than three percent.
We calculated the genetic distances and plot multidimensional scaling, comparing the gene pools of the studied genus with other tribes of the Eurasian steppe from the frequencies of haplogroups. Tribe Argyn took on graph an isolated position, demonstrating the absence of genetic links with other Kazakh tribes.
The European Society of Human Genetics 2013
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