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Prg Sch at a Glance
Initial Experience Using A Collagen Matrix Implant (Ologen
) As A Wound Modulator With Canaloplasty: 12 Month Results
Presentation Start/End Time:
Monday, May 07, 2012, 3:45 PM - 5:30 PM
Surgical Wound Healing
203 glaucoma: surgery or wound healing - GL
Matthew S. Johnson
, Steven Sarkisian
, Nathan Blessing
, James M. Rouse
Ophthalmology, Dean McGee Eye Institute, Oklahoma City, OK;
Ophthalmology, Oklahoma University Health Science Center, Oklahoma City, OK.
630 outflow: trabecular meshwork, 761 wound healing
To investigate the success rate of a collagen matrix implant as a wound modulator in canaloplasty.
A retrospective review was performed of 22 consecutive eyes with 12 months of follow up data after undergoing canaloplasty using collagen in the scleral lake. Main outcome measures included post-operative IOP, number of anti-glaucoma medications, and post-operative complications. Complete surgical success was defined as an IOP ≤ 21, 18, and 16 mm Hg without medications, and qualified success with or without medications.
The mean IOP dropped from 23.0 ± 7.0 mm Hg preoperatively to 13.4 ± 3.3 mm Hg at 12 months. Mean number of medications dropped from 1.8 ± 1.0 preoperatively to 0.59 ± 0.85 at 12 months. Complete surgical success was achieved in 54.5% of patients, all of whom had an IOP ≤ 16 mm Hg. The qualified success rate of an IOP ≤ 21, 18, and 16 mm Hg was 100%, 95.5%, and 72.7%, respectively. Post-operative complications included transient conjunctival leaks in 6 eyes, shallow anterior chamber in 1 eye, and bleb formation in 1 eye. Post-operative interventions included laser goniopuncture performed in 5 eyes, iridoplasty performed in 1 eye, and bleb revision performed in 1 eye. Mean IOP before goniopuncture was 32.4 ± 19.3 mmHg, and was 17.6 ± 7.9 mm Hg on the subsequent post-procedure visit.
Surgical success indicates a collagen matrix implant may be a useful adjunct in canaloplasty.
Matthew S. Johnson
, iScience (C), Optous (C);
James M. Rouse
This research was supported in part by Research to Prevent Blindness
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