Presentation Abstract

Program#/Poster#: 2508/A234
Abstract Title: Initial Experience Using A Collagen Matrix Implant (OlogenTm) As A Wound Modulator With Canaloplasty: 12 Month Results
Presentation Start/End Time: Monday, May 07, 2012, 3:45 PM - 5:30 PM
Session Number: 290
Session Title: Surgical Wound Healing
Location: Hall B/C
Reviewing Code: 203 glaucoma: surgery or wound healing - GL
Author Block: Matthew S. Johnson1, Steven Sarkisian1, Nathan Blessing2, James M. Rouse1. 1Ophthalmology, Dean McGee Eye Institute, Oklahoma City, OK; 2Ophthalmology, Oklahoma University Health Science Center, Oklahoma City, OK.
Keywords: 630 outflow: trabecular meshwork, 761 wound healing
Abstract Body: Purpose: To investigate the success rate of a collagen matrix implant as a wound modulator in canaloplasty.
Methods: A retrospective review was performed of 22 consecutive eyes with 12 months of follow up data after undergoing canaloplasty using collagen in the scleral lake. Main outcome measures included post-operative IOP, number of anti-glaucoma medications, and post-operative complications. Complete surgical success was defined as an IOP ≤ 21, 18, and 16 mm Hg without medications, and qualified success with or without medications.
Results: The mean IOP dropped from 23.0 ± 7.0 mm Hg preoperatively to 13.4 ± 3.3 mm Hg at 12 months. Mean number of medications dropped from 1.8 ± 1.0 preoperatively to 0.59 ± 0.85 at 12 months. Complete surgical success was achieved in 54.5% of patients, all of whom had an IOP ≤ 16 mm Hg. The qualified success rate of an IOP ≤ 21, 18, and 16 mm Hg was 100%, 95.5%, and 72.7%, respectively. Post-operative complications included transient conjunctival leaks in 6 eyes, shallow anterior chamber in 1 eye, and bleb formation in 1 eye. Post-operative interventions included laser goniopuncture performed in 5 eyes, iridoplasty performed in 1 eye, and bleb revision performed in 1 eye. Mean IOP before goniopuncture was 32.4 ± 19.3 mmHg, and was 17.6 ± 7.9 mm Hg on the subsequent post-procedure visit.
Conclusions: Surgical success indicates a collagen matrix implant may be a useful adjunct in canaloplasty.
CommercialRelationships:  Matthew S. Johnson, None; Steven Sarkisian, iScience (C), Optous (C); Nathan Blessing, None; James M. Rouse, None
Support: This research was supported in part by Research to Prevent Blindness



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